Top Cortisol Detox Supplements For Menopause Weight Support

Updated: November 2025

Midlife weight gain, mood swings, and fatigue? Often, it’s not just menopause – it’s cortisol overload. As hormones shift, stress levels rise, making it harder to lose weight and feel like yourself. That’s why more women are turning to natural supplements that target both cortisol and menopause symptoms. We reviewed the most popular menopause supplements – not just for symptom relief, but for their ability to target cortisol, the hormone at the root of so many midlife struggles. See the top picks for women 40+.

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Her Bodhi

Ranked #1 out of 6

4.8 / 5

Her Bodhi is our top pick for cortisol balance and menopause support. It features KSM-66® Ashwagandha – clinically shown to lower cortisol by up to 32% – to help ease stubborn weight, fatigue, and mood swings. 100% natural, hormone-free, and trusted by over 58,000 clients.

  • ​​Helps reduce hot flashes and night sweats

  • Helps lower cortisol levels to combat hormonal belly fat

  • Aids, sustainable weight loss

  • Promotes deeper, more restful sleep

  • Eases stress and anxiety naturally

  • Helps relieve vaginal dryness and discomfort

$20.67 

/bottle

info

Last price update:

August 27, 2025

Visit Her Bodhi Detailed Information

Her Bodhi is our top pick for cortisol balance and menopause support. It features KSM-66® Ashwagandha – clinically shown to lower cortisol by up to 32% – to help ease stubborn weight, fatigue, and mood swings. 100% natural, hormone-free, and trusted by over 58,000 clients.

Available on

Detailed Information

Happy Mammoth

Ranked #2 out of 6

4.6 / 5

Happy Mammoth's supplements could be a great addition to your routine. They are designed to support your body’s natural hormone production and regulation processes. Featuring a blend of natural ingredients, these supplements help you manage estrogen levels, reduce irritability, and feel more like yourself again.

  • Decreases symptoms of premenstrual tension

  • Supports reproductive hormones

  • Relieves mild gastrointestinal tract discomfort

  • Supports cortisol, progesterone, and estrogen levels

  • Promotes better sleep

$69.99 

/bottle

info

Last price update:

August 27, 2025

Visit Happy Mammoth Detailed Information

Happy Mammoth's supplements could be a great addition to your routine. They are designed to support your body’s natural hormone production and regulation processes. Featuring a blend of natural ingredients, these supplements help you manage estrogen levels, reduce irritability, and feel more like yourself again.

Available on

Detailed Information

OPositiv

Ranked #3 out of 6

4.5 / 5

MENO by OPositiv is on a mission to make effective, fun, and delicious products that address historically overlooked female health needs. Their symptom-targeted products are aimed not only at easing common menopause symptoms but also to help regain confidence in your body with their science-backed formula.

  • Hormone-free menopause support

  • Enhances mood

  • Multi-symptom menopause relief

  • Promotes restful sleep

  • Includes essential vitamins for energy support

$42.99 

/month

info

Last price update:

August 27, 2025

Visit Opositiv Detailed Information

MENO by OPositiv is on a mission to make effective, fun, and delicious products that address historically overlooked female health needs. Their symptom-targeted products are aimed not only at easing common menopause symptoms but also to help regain confidence in your body with their science-backed formula.

Available on

Detailed Information

Estroven

Ranked #4 out of 6

4.3 / 5

When menopause hits, it can feel like your body is betraying you. Estroven is here to help you reclaim your comfort and confidence. This multi-symptom supplement is specially formulated to ease the most common menopausal symptoms, so you can enjoy your life as you used to.

  • Reduces hot flashes and night sweats

  • Supports energy levels

  • Enhances mood

  • Promotes restful sleep

  • Free of both estrogen and other hormones, non-GMO

$29.99 

/month

info

Last price update:

August 27, 2025

Visit Estroven Detailed Information

When menopause hits, it can feel like your body is betraying you. Estroven is here to help you reclaim your comfort and confidence. This multi-symptom supplement is specially formulated to ease the most common menopausal symptoms, so you can enjoy your life as you used to.

Available on

Detailed Information

Amberen

Ranked #5 out of 6

4.1 / 5

Amberen empowers you to take control of your perimenopause and menopause journey. With its proprietary formula, Amberen provides comprehensive relief from the physical and emotional symptoms of menopause, allowing you to experience life-transforming comfort and wellness.

  • Reduces hot flashes and night sweats

  • Balances mood

  • Boosts energy levels and reduces fatigue

  • Helps to regulate hormone production

$29.99 

/per pack

info

Last price update:

August 27, 2025

Visit Amberen Detailed Information

Amberen empowers you to take control of your perimenopause and menopause journey. With its proprietary formula, Amberen provides comprehensive relief from the physical and emotional symptoms of menopause, allowing you to experience life-transforming comfort and wellness.

Available on

Detailed Information

Provitalize

Ranked #6 out of 6

3.9 / 5

Provitalize by Better Body Co is a supplement designed to help women stay cool, active, and look fabulous in their 40s & beyond. This probiotic blend aims to enhance metabolism, reduce inflammation, and improve gut health while supporting weight management efforts.

  • Supports healthy abdominal fat management

  • Balances estrogen level

  • Provides menopause inflammation support

  • Reduces bloating

$39.75 

/bottle

info

Last price update:

August 27, 2025

Visit Provitalize Detailed Information

Provitalize by Better Body Co is a supplement designed to help women stay cool, active, and look fabulous in their 40s & beyond. This probiotic blend aims to enhance metabolism, reduce inflammation, and improve gut health while supporting weight management efforts.

Available on

Detailed Information
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Editor’s choice: best hormonal support supplements on the market today

Her Bodhi

4.8

Visit Her Bodhi

Editor’s review

Her Bodhi stands out as the most complete formula for cortisol reduction and menopause support, delivering the full 600 mg clinical dose of KSM-66® Ashwagandha. With added botanicals for hormone balance, metabolism, and inflammation, it’s the most targeted solution for midlife women facing stress-related weight gain and fatigue.

  • ​​Helps reduce hot flashes and night sweats

  • Helps lower cortisol levels to combat hormonal belly fat

  • Aids, sustainable weight loss

  • Promotes deeper, more restful sleep

  • Eases stress and anxiety naturally

  • Helps relieve vaginal dryness and discomfort

Happy Mammoth

4.6

Visit Happy Mammoth

Editor’s review

Happy Mammoth offers strong cortisol and mood support with 600 mg of KSM-66® Ashwagandha and a calming blend of adaptogens. It’s ideal for emotional balance and stress relief during menopause, though less targeted for metabolism or hormonal weight changes.

  • Decreases symptoms of premenstrual tension

  • Supports reproductive hormones

  • Relieves mild gastrointestinal tract discomfort

  • Supports cortisol, progesterone, and estrogen levels

  • Promotes better sleep

OPositiv

4.5

Visit Opositiv

Editor’s review

MENO by OPositiv blends key ingredients like Black Cohosh and 300 mg of KSM-66® Ashwagandha to ease mood swings, hot flashes, and stress. While it offers light cortisol support, the adaptogen dose falls below clinically effective levels for full hormonal reset.

  • Hormone-free menopause support

  • Enhances mood

  • Multi-symptom menopause relief

  • Promotes restful sleep

  • Includes essential vitamins for energy support

Choosing the best diet plans: how we rank and compare them

Personalization

We believe each diet plan should be unique the way you are. The diet providers determination and processes are needed to evaluate personal factors. This is critical to get a high rating and appear at the top of the list.

Goal Orientation

Changing your nutrition is a challenge. Therefore, you need great support and a motivational system to keep you engaged and concentrated on the goal. Celebrating milestones is linked to your overall success and satisfaction levels. This is the deepest criteria category with menu different possibilities to make you succeed.

Diet Friendliness

Nobody wants to follow a diet plan that is impossible. A number of different recipes to suit, varying difficulty, preparation tutorials, and a grocery list to help simplify the shopping experience.

Pricing

Good service comes at a certain price which should be reasonable and competitive. Additionally, various payment methods, a transparent cancellation policy, and a smooth refund process are all vitally important.

Support

On your journey to a healthier you, different questions and issues might arise when you least expect them. Thus great support infrastructure on general, nutrition, sports activity questions is important for a smooth experience.

Reliability

We believe that great service should not compromise your personal data and privacy. Especially when it comes to your health data.